Catalyst Grant

Agentic workflows you can trust

Announcing the 2026 Catalyst Grant theme

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AI that acts on research. Trust that travels with it.

AI is starting to do research, not just describe it. The next breakthroughs will come from agentic workflows, autonomous and multi-step, that researchers, institutions and funders can actually rely on. For 2026, we are backing the early-stage tools, agents and platforms making that real: AI that acts on research, embedded in the workflows it serves, with provenance, governance and accountability built in.

What is the Catalyst Grant?

The Digital Science Catalyst Grant is an international initiative to support innovation in new software tools and technologies to advance research and create meaningful change.  The program supports and invests in early-stage ideas in the novel use of technology with an award of up to £25,000 for the most promising ideas that aid science and further its impact on society.

Who we’re looking for

We want early-stage startups, research projects and moonshot thinkers building agentic tools that:

  • Operate across multiple steps, planning, executing and reviewing, rather than answering a single prompt
  • Embed in the workflows researchers, institutions and publishers already use
  • Carry audit trails, governance controls and provenance, so the people who rely on them can trust them
  • Tackle a real problem across the research lifecycle: writing, discovery, evidence synthesis, peer review, funding decisions or research integrity

For example, tools working in these areas:

  • Trusted authorship and writing. AI co-writers with transparent contribution logs, autonomous citation and source verification agents, or cryptographic authorship attestation for high-stakes academic work
  • Enterprise research workflows. Regulatory-grade evidence synthesis agents, governed knowledge graph workflows with provenance at every step, or explainable drug discovery and target identification tools
  • Funding and institutional decisions. Researcher identity and disambiguation agents, automated reviewer matching and COI screening, or grant-portfolio intelligence for programme officers
  • Publication integrity. Auditable manuscript screening, citation and figure provenance verification, or multi-step editorial workflow agents with full audit trails

If you’re making AI safe to put in front of an institution,  autonomous in service of researchers, with accountability built in, we want to hear from you.

Why apply

The award is up to £25,000, but the grant’s real value is the conversations it starts. Our team comes from research and research software, with decades of experience between us. Most applicants do not win an award, but they can come away with advice, introductions and a sharper idea. We invest in the community because we come from it.

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How to test your idea before applying

  1. Name the research decision your agent affects, and who makes it today (who, when, how often).
  2. Say where it sits in the research lifecycle: writing, discovery, evidence synthesis, peer review, funding decisions or research integrity. If it isn’t one of these, it probably isn’t a fit this year.
  3. Name the tool or system it has to live inside, and who already uses that tool every day. We are more interested in something embedded in real work than a standalone demo.
  4. Check the work genuinely needs more than one step. If a single well-written prompt does the job, it isn’t an agentic workflow.
  5. Test where it breaks. Give it a task it should refuse, flag or escalate, and record what actually happened.
  6. Name your outcome metric, for example reviewer hours saved, time to funding decision, or duplicate work avoided.

How to enter

Applying takes one short form and a few minutes.

Who can apply. Anyone with an early-stage idea: founders, research teams, students and individuals. Your tool can be a prototype, a working product or a well-formed concept. We fund early, so you do not need revenue or a finished build.

What to tell us. A clear description of the problem you are solving, your approach, why it fits an agentic, trustworthy workflow, and where you are today. If you have a demo or prototype, show us.

How we choose. Our judges score each application across seven areas: team, problem, solution, competitors, market, progress to date, and fit with Digital Science. Strong applicants are invited to a short interview with a live demo (where applicable) and a few questions.

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Key dates

  • Applications open: Tuesday 1st September 2026
  • Applications close: Monday 5th October 2026, 17:00 BST
  • Judging: Monday 12th October to Friday 20th November 2026
  • Winners announced: week commencing Monday 30th November 2026

The award. Up to £25,000, which can be split across more than one recipient.

View past winners

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Hear from previous winners

Resource Library

Reach out

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Steve Scott, VP Portfolio Development