Featured Resource: New agile methods to extract deeper knowledge
Find out how we provide an open and iterative approach by connecting our tools with those of the research community. We develop special functions within a matter of days allowing you to implement a search strategy, connect with a diverse range of data sources and so much more.
Providing valuable data on funding flows for market model development
Find out how Illumina uses Dimensions to understand trends in academic funding, KOL identification and to find leads for sales.
“ It is really beneficial to be able to use the same keywords across the 3 different content types – grants, pubs and clinical trials – in one platform.”Aruna Rajan, Staff Market Research Analyst, Illumina
Getting started with Dimensions L&C
In this video learn how to run semantic search in Dimensions L&C to get a list of precise and comprehensive results. We will also explore the ontological tree within Dimensions L&C, which contains over 40 million concepts related to life sciences and chemistry, and finally we will see a quick overview of the analytical and search tools Dimensions L&C has to offer.
Generate insights quicker using Co-occurrence Analysis
In this video learn how to run a Co-occurrence Analysis in Dimensions L&C, a powerful tool which enables you to generate insights from millions of scientific documents within seconds. We will explore general and specific use cases for this function to enable you to get the most out of Dimensions L&C.
Understand disease mechanisms
In this video learn how to use “co-occurrence analysis” in Dimensions L&C to get a better understanding of disease mechanisms. We will generate insights from hundreds of millions of scientific documents by correlating a disease with semantic concepts – such as signalling pathways, genes & proteins and pathophysiological processes – to quickly generate hypotheses on disease mechanisms, which is an important first step in drug target identification and the drug development process in general.
Understand drug candidate mechanisms of action
In this video learn how to use “chemistry search” to discover chemical compounds similar to your drug candidate or containing a specific chemical substructure of your interest. We will run a comprehensive search to identify documents, such as patents, publications, grants and clinical trials, that mention relevant compounds and apply a powerful semantic concepts extraction analysis to generate insights on the compounds’ mechanisms of action and therapeutic applications.
Clarify the mechanism of action
To select the best therapeutic application for repositioning a known drug or avoid undesirable adverse events for novel compounds, it is critical to have a clear understanding how the drug or compound works.
To uncover these insights, you need to find and analyze all information available on a drug/compound or those similar to it. The powerful semantic search of Dimensions L&C allows you to search through 40 million concepts, including new compounds, approved drugs, genes, and proteins alongside chemistry search and co-occurrence analysis. This enables you to identify more relevant documents and gain deeper insights about drug and compound connections to proteins, disease, signalling pathways, pathophysiology, and toxicities.
Analyze disease mechanisms
Understanding target and disease biology is crucial for success when bringing a new drug to market. However, the data supporting this understanding is spread across hundreds of thousands and millions of scientific documents, including publications, patents, grants, and clinical trials. Dimensions L&C provides a powerful semantic search with up to 40 million concepts that incorporate genes, proteins and diseases, derived from hundreds of millions of scientific documents, together with co-occurrence analysis.
This enables you to quickly discover more relevant documents and gain deeper insights regarding disease mechanisms and the connections between diseases, proteins, signalling pathways, and biological processes in a real-time.
Identify drug targets
Identification of a “right” drug target is a critical step in drug development that helps to avoid later stage failures of drug candidates in clinical trials. To make an evidence-based decision on drug targets, a compilation and analysis of multiple scientific documents are required.
Dimensions L&C provides a powerful semantic search of up to 40 million concepts, including genes & proteins, diseases and corporate information, together with co-occurrence analysis. This enables you to rapidly discover more relevant documents and gain deeper insights as to potential drug targets and their connections to diseases, drugs, biological and pathological processes, and commercial potential in a real time.
Driving Innovation & Collaboration Across Boehringer Ingelheim
In this case study, Dr. Karlheinz Spenny and his team at the SIC share what triggered their internal innovation campaign to move from their legacy literature management solution to the Enterprise edition of ReadCube Papers and their experiences along the way.
- Factors driving the switch from BI’s legacy literature management/citation tool
- Why BI chose ReadCube Papers Enterprise
- Preparing for & managing change through transition
- The rollout & reactions
- Standout features
- Reflections post-deployment
“What we have achieved within just 7 months after the roll-out of ReadCube Papers can only be considered a jump to the next level of literature management for our research scientists and has positioned BI as front-runners within our industry.”Dr. Karlheinz Spenny, Boehringer Ingelheim
Navigating Networks Of Oncology Biomarkers
Using large-scale analytics of published literature, biomarkers across six cancer types were successfully characterized in terms of their emergence in the published literature and the context in which they are described.
This novel approach could help identify biomarkers and biomarker panels, which may be otherwise missed through traditional search methods, for expert review and exploration in a clinical setting.
Research is continually evolving and dynamics within and between fields change constantly. Landscape assessments ensure you understand the lay of the land and are prepared to adapt to change. Our analysts use Dimensions to help you:
- Identify major global research areas.
- Understand how scientific fields are changing.
- Assess emerging trends within a specific field of study.
- Recognize the experts in these fields.
Enhancing your Gap Analysis with Machine Enhanced Literature Retrieval
Dimensions data can be used to enhance your literature gap analysis. Dimensions is particularly suitable for performing literature gap analyses on a large scale, combining standard abstract searches with high precision full-text queries and subsequent aggregation. This allows creating heat maps on numbers of publications for combinations of terms, e.g., drugs versus adverse events, with the option to directly view the set of publications for a particular combination. Such an approach takes minutes to run and can be repeated to track changes over time.
Real word databases identification
While real-world databases are of increasing interest to researchers, there is no comprehensive dataset listing all real-world databases. We have created an algorithm which finds publications presenting real-world databases:
- Several search methods were applied to select articles which present research using real world databases
- Publications were identified which were frequently cited by the above articles, to arrive at the initial publications announcing real world databases
- With this approach the number of known real world databases could be doubled
How to Run Your Biotech R&D Virtually
Hire more people, take your groundbreaking data and hit milestones in just 3 steps! We provide a suite of research solutions to hire, store and share data across your companies to make your research efficient and cost-effective. Anyone working in a lab will benefit from this session.
Pinpointing Global Expertise In Non-Alcoholic Fatty Liver Disease
Disease types associated with NAFLD present a tremendous research and development challenge for life sciences organizations and also a great opportunity for them to create value and innovation. Find out how Digital Science offers the data capabilities to help you uncover insights and expertise in disease-related topics and key indication areas.
Identifying Global Expertise in CAR-T-time data
Digital Science offers data capabilities and the connected data to help life science organizations understand the Car-T research and development landscape. Find out how Digital Science offers the data capabilities to help you uncover insights and expertise in disease-related topics and key indication areas.
Measuring the value of medical affairs
As a medical affairs professional or publications planner in the pharmaceutical industry, we understand that you need to demonstrate the impact of the work you do. Download our whitepaper today to find out how altmetrics can help you.
Get better insights for medical affairs
Spend less time searching for the right information and more time acting on it. Dimensions is a comprehensive discovery and analytics platform with millions of data points, and an ideal information source for medical affairs professionals.
Finding the right experts just got easier
Since finding KOLs is a frequently performed and important activity, the Dimensions team created a new tool that makes it even easier. It features a simple and intuitive user interface that accesses all of the data Dimensions has to offer.